P03-004 - Production of proinflammatory cytokines in PFAPA
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چکیده
منابع مشابه
P03-004 - Production of proinflammatory cytokines in PFAPA
Introduction The PFAPA syndrome, associated with aphthous stomatitis, pharyngitis and cervical adenitis which is characterized by monthly flare-ups of fever is quite common in early childhood. Affected children experience their first attack before the age of 5, with fever episodes usually abating in adolescence or young adulthood. Usually a single administration of oral corticosteroids aborts a...
متن کاملP03-001 - PFAPA and MEFV genes
Introduction Marshall Syndrome or PFAPA is an inflammatory periodic disease characterized by periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis. Restless, headache, abdominal pain, vomiting, hepatosplenomegaly and arthralgia are less common symptoms seeing in this disease. The diagnosis is established on the basis of clinical criteria that require the presence of a recurrent...
متن کاملP03-005 - MEFV heterozygous mutations in PFAPA patients
Introduction PFAPA syndrome (acronym for periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis) is the most common cause of periodic fever in childhood. It is considered part of the wide family of the autoinflammatory diseases, but a genetic or molecular marker hasn’t been identified yet, therefore, its etiology is still unknown. Diagnosis is essentially based on clinical crite...
متن کاملInhibition of Nitric Oxide Production and Proinflammatory Cytokines by Several Medicinal Plants
Background: A number of medicinal plants have been used to treat various immunological diseases. Nitric oxide (NO) has an important regulatory role in the various types of inflammatory processes. Objective: To investigate the NO modulatory activity of the extracts of several medicinal plants native to Iran including Dracocephalum kotschyi, Linum persicum, Dionysia termeana, Salvia mirzayanii, F...
متن کاملPW03-004 - PFAPA patient’s serum sensitizes monocytes to LPS
Methods Serum of three controls (CTRL) or PFAPA patients collected during (PFAPA-IN) and between (PFAPA-OUT) flares were incubated with monocytes isolated from healthy volunteers (n=3) and stimulated with ultra pure lipopolysaccharide (LPSup). IL-1b, TNF-a and IL-6 levels were measured by ELISA comparing serum stimulation alone and the impact of serum pre-incubation on LPSup induced cytokines.
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ژورنال
عنوان ژورنال: Pediatric Rheumatology
سال: 2013
ISSN: 1546-0096
DOI: 10.1186/1546-0096-11-s1-a199